Risk prediction models for endometrial cancer: development and validation in an international consortium

January 2023
Journal of the National Cancer Institute

Joy Shi, Peter Kraft, Bernard A. Rosner, Yolanda Benavente, Amanda Black, Louise A. Brinton, Chu Chen, Megan A. Clarke, Linda S. Cook, Laura Costas, Luigino Dal Maso, Jo L. Freudenheim, Jon Frias-Gomez, Christine M. Friedenreich, Montserrat Garcia-Closas, Marc T. Goodman, Lisa Johnson, Carlo La Vecchia, Fabio Levi, Jolanta Lissowska, Lingeng Lu, Susan E. McCann, Kirsten B. Moysich, Eva Negri, Kelli O’Connell, Fabio Parazzini, Stacey Petruzella, Jerry Polesel, Jeanette Ponte, Timothy R. Rebbeck, Peggy Reynolds, Fulvio Ricceri, Harvey A. Risch, Carlotta Sacerdote, Veronica W. Setiawan, Xiao-Ou Shu, Amanda B. Spurdle, Britton Trabert, Penelope M. Webb, Nicolas Wentzensen, Lynne R. Wilkens, Wang Hong Xu, Hannah P. Yang, Herbert Yu, Mengmeng Du, Immaculata De Vivo

We develop and externally validate risk prediction models for endometrial cancer based on epidemiologic risk factors and epidemiologic plus genetic risk factors.

Effect of colonoscopy screening on risks of colorectal cancer and related death

October 2022
New England Journal of Medicine

Michael Bretthauer, Magnus Løberg, Paulina Wieszczy, Mette Kalager, Louise Emilsson, Kjetil Garborg, Maciej Rupinski, Evelien Dekker, Manon Spaander, Marek Bugajski, Øyvind Holme, Ann G. Zauber, Nastazja D. Pilonis, Andrzej Mroz, Ernst J. Kuipers, Joy Shi, Miguel A. Hernán, Hans-Olov Adami, Jaroslaw Regula, Geir Hoff, and Michal F. Kaminski, for the NordICC Study Group

We present the results from the NordICC trial, a pragmatic, randomized trial involving men and women aged 55 to 64 years of age from Poland, Norway, Sweden, and the Netherlands between 2009 and 2014 who were randomized to receive an invitation to undergo a single screening colonoscopy or to receive no invitation or screening.

Instrumental variable estimation for a time-varying treatment and a time-to-event outcome via structural nested cumulative failure time models

November 2021
BMC Medical Research Methodology

Joy Shi, Sonja A. Swanson, Peter Kraft, Bernard Rosner, Immaculata De Vivo, and Miguel A. Hernán

We propose the use of g-estimation of structural nested cumulative failure time models for instrumental variable analyses of time-varying exposures and failure time outcomes.

Lifetime moderate-to-vigorous physical activity and ER/PR/HER-defined post-menopausal breast cancer risk

June 2017
Breast Cancer Research and Treatment

Joy Shi, Lindsay C. Kobayashi, Anne Grundy, Harriet Richardson, Sandip K. SenGupta, Caroline A. Lohrisch, John J. Spinelli, Kristan J. Aronson

We examine relationships between moderate-to-vigorous physical activity across different domains during the lifetime on risk of breast cancer subtypes.

Polymorphisms of insulin-like growth factor 1 pathway genes and breast cancer risk

June 2016
Frontiers in Oncology

Joy Shi, Kristan J. Aronson, Anne Grundy, Lindsay C. Kobayashi, Igor Burstyn, Johanna M. Schuetz, Caroline A. Lohrisch, Sandip K. SenGupta, Agnes S. Lai, Angela Brooks-Wilson, John J. Spinelli, Harriet Richardson

Relationships between genetic variants of insulin-like growth factor 1 (IGF1) pathway genes and breast cancer risk are assessed.

Genetic variation in vitamin D-related genes and risk of breast cancer among women of European and East Asian descent

Tumour Biology
December 2015

Joy Shi, Anne Grundy, Harriet Richardson, Igor Burstyn, Johanna M. Schuetz, Caroline A. Lohrisch, Sandip K. SenGupta, Agnes S. Lai, Angela Brooks-Wilson, John J. Spinelli, Kristan J. Aronson

Relationships between genetic variants of vitamin D-related genes and breast cancer risk are assessed.